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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZFHX4
All Species:
16.36
Human Site:
S464
Identified Species:
40
UniProt:
Q86UP3
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86UP3
NP_078997.3
3567
393730
S464
N
G
E
C
P
V
K
S
E
P
T
E
P
G
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001089817
3156
348587
D244
E
K
D
Y
L
T
S
D
G
S
A
K
N
S
C
Dog
Lupus familis
XP_853266
3452
379865
S464
N
G
E
C
P
V
K
S
E
P
T
E
A
G
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJN2
3550
392304
S463
N
V
G
C
P
V
K
S
E
P
T
E
P
G
D
Rat
Rattus norvegicus
XP_226964
3593
395739
S465
N
G
E
C
P
I
K
S
E
P
N
E
P
G
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509863
3710
407348
C493
E
E
E
E
D
E
G
C
K
G
L
F
P
S
E
Chicken
Gallus gallus
O73590
3573
394529
S464
N
G
E
F
P
I
K
S
E
P
T
E
P
V
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_684360
2686
299027
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393785
2962
326678
E50
Y
I
I
E
G
E
S
E
L
S
E
D
D
S
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798150
3296
366823
Q384
Q
P
P
G
G
L
G
Q
S
V
Y
S
S
A
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
87.1
90.4
N.A.
90.8
91.8
N.A.
55.3
90.2
N.A.
52.6
N.A.
N.A.
21.1
N.A.
26
Protein Similarity:
100
N.A.
87.6
92.4
N.A.
94.1
94.9
N.A.
68.1
94
N.A.
61.7
N.A.
N.A.
36.2
N.A.
41.1
P-Site Identity:
100
N.A.
0
93.3
N.A.
86.6
86.6
N.A.
13.3
73.3
N.A.
0
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
100
N.A.
13.3
93.3
N.A.
86.6
93.3
N.A.
26.6
86.6
N.A.
0
N.A.
N.A.
6.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
10
0
10
10
0
% A
% Cys:
0
0
0
40
0
0
0
10
0
0
0
0
0
0
10
% C
% Asp:
0
0
10
0
10
0
0
10
0
0
0
10
10
0
40
% D
% Glu:
20
10
50
20
0
20
0
10
50
0
10
50
0
0
20
% E
% Phe:
0
0
0
10
0
0
0
0
0
0
0
10
0
0
0
% F
% Gly:
0
40
10
10
20
0
20
0
10
10
0
0
0
40
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
10
0
0
20
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
0
0
0
50
0
10
0
0
10
0
0
0
% K
% Leu:
0
0
0
0
10
10
0
0
10
0
10
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
50
0
0
0
0
0
0
0
0
0
10
0
10
0
10
% N
% Pro:
0
10
10
0
50
0
0
0
0
50
0
0
50
0
0
% P
% Gln:
10
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
20
50
10
20
0
10
10
30
0
% S
% Thr:
0
0
0
0
0
10
0
0
0
0
40
0
0
0
0
% T
% Val:
0
10
0
0
0
30
0
0
0
10
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
10
0
0
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _